Christopher and Madonna worked together for a long time.

Madonna's younger brother Christopher Ciccone - who worked closely with the Queen of Pop throughout her career - has died.

Christopher Ciccone died of cancer at age 63.

Oct. 6 (UPI) -- Pop music icon Madonna's brother Christopher Ciccone has died of cancer at the age of 63, two weeks after their 81-year-old stepmother, Joan Clare Ciccone, passed away from the same disease.

Madonna is mourning the loss of her brother Christopher Ciccone, who sadly died at the age of 63, just days after their stepmother Joan Clare Ciccone passed away.

Music icon Madonna has lost her younger brother, Christopher Ciccone, who worked as a designer, artist and director throughout his career organizing concert tours, music videos, and film, to commercial, residential interior and furniture design

Christopher Ciccone worked closely with his sister during the early years of their careers