Colorado vs. Kansas State prediction, odds, props: 2024 college football expert picks, Deion Sanders best bets

SportsLine expert Jimmie Kaylor revealed his CFB picks, Big 12 predictions and props for the K-State Wildcats vs. CU Buffaloes game featuring Shedeur Sanders and Travis Hunter

Deion Sanders and the Colorado Buffaloes (4-1, 2-0) look to stay unbeaten in Big 12 play when they host the No. 18 Kansas State Wildcats (4-1, 1-1) on Saturday at Folsom Field. Both teams will be coming off bye weeks and should be well rested. The Buffs pulled off a massive upset in their outing, notching a 48-21 road win over UCF behind big performances from Shedeur Sanders and Travis Hunter. The Wildcats beat Oklahoma State 42-20 in their last game, bouncing back nicely from a loss to BYU the previous week. CU leads the all-time series 45-20-1.

Kickoff in Boulder is scheduled for 10:15 p.m. ET. The Wildcats are 3.5-point favorites in the latest Colorado vs. Kansas State odds via SportsLine consensus, and the over/under is 55.5 points. Before making any Kansas State vs. Colorado picks, you need to see the Week 7 college football predictions and betting advice from SportsLine's Jimmie Kaylor. 

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor destroyed the books in college football in 2023, netting a whopping 57.9 units while posting a 107-45-2 record. Anyone who followed his picks finished the season way up.

Now, Kaylor has dialed in on Colorado vs. Kansas State on Saturday and just revealed his picks and predictions. You can head to SportsLine now to see his picks. Here are the college football odds and college football betting lines on the spread, money line, and over/under for K-State vs. Colorado:

• Colorado vs. Kansas State spread: Kansas State -3.5
• Colorado vs. Kansas State over/under: 55.5 points 
• Colorado vs. Kansas State money line: Kansas State -163, Colorado +135
• Colorado vs. Kansas State picks: See picks at SportsLine
• Colorado vs. Kansas State streaming: FuboTV (try for free)

Why Kansas State can cover

The Wildcats have one of the top rushing attacks in college football. Junior running back DJ Giddens has led the way, and enters Saturday with 604 yards and two touchdowns on 86 carries. Colorado transfer Dylan Edwards has been a nice change of pace back for K-State, rushing for 201 yards and two touchdowns.

Defensively, the Wildcats rank near the top of the Big 12, allowing 19.6 points per game this season. Linebacker Austin Romaine leads the team in tackles (34), and has also contributed 2.0 sacks. 6-foot-5 senior defensive end Brendan Mott has been a menace off the edge for K-State, racking up four sacks thus far. See which team to pick here.

Why Colorado can cover

The Buffs have made significant strides as a program in year two under Coach Prime. Colorado has already matched last year's win total, and is now only two victories away from locking up bowl eligibility. CU is 3-0 against the spread in its last three games.

Quarterback Shedeur Sanders has been outstanding for the Buffs in his second year in Boulder. The 6-foot-2 senior is widely regarded as one of the best quarterbacks in the country, and is a potential top-10 pick in the 2025 NFL Draft. In 2024, Sanders has completed 70.1% of his passes for 1,630 yards, 14 touchdowns and three interceptions. He's added 25 yards and a touchdown on the ground. See which team to pick here.

How to make Kansas State vs. Colorado picks

Kaylor has analyzed Colorado vs. Kansas State from every angle and he's leaning Over on the point total. He has also discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing what it is, and which side to back, at SportsLine.

So who wins Colorado vs. Kansas State on Saturday night in Boulder, and what critical X-factor makes one side of the spread a must back? Visit SportsLine now to see which side of the spread to jump on, all from the expert who profited $5,790 for $100 college football bettors in 2023, and find out.