Week 4 NFL trends, predictions, bets, odds: Sharp money picks from professional football bettors in Las Vegas

Sportsbook veterans and Las Vegas insiders reveal sharp money against the spread NFL picks from respected pro football bettors

The NFL Week 4 schedule features four division-rivalry games, headlined by Chiefs vs. Chargers and Vikings vs. Packers. The undefeated Chiefs will put their perfect record on the line when they travel to Los Angeles. Chargers quarterback Justin Herbert (ankle) is banged-up, which has led to Kansas City being favored by 7.5 points in the latest Week 4 NFL odds, with an over/under of 41.5 points. Meanwhile, the Packers (2-1) are 3-point favorites over the Vikings (3-0) with an over/under of 44 points in the NFL Vegas lines for their game at Lambeau Field. Are the NFL sharp money bettors in Las Vegas targeting either game with their NFL Week 4 picks? Before making NFL Week 4 picks or bets, you need to see the NFL against the spread picks from the sharp money gamblers and professional football bettors in Las Vegas.

Sharp money bettors are notorious in Las Vegas for finding value in point spreads and betting lines that casual bettors may not see. These professional bettors are respected by sportsbooks in Vegas and all around the world, and their betting action often causes bookmakers to change their lines. 

Jay Kornegay, EVP of the Westgate SuperBook in Las Vegas, joined SportsLine NFL expert Jimmie Kaylor to share who the Vegas sharps are backing in the Week 3 NFL odds. Kornegay is a longtime oddsmaker at the SuperBook, and has been a key player on the Vegas bookmaking scene for more than 25 years. He was inducted into the Sports Betting Hall of Fame Class of 2024.

Now that the sharps in Las Vegas have had a chance to digest the Week 3 NFL odds, they've start to lock in their picks for the Week 3 NFL schedule. You can only see them by heading to SportsLine.

Top Vegas NFL sharp money picks for Week 4

For Week 4, one of the Sharp Money plays the SuperBook has taken is the Detroit Lions (-3.5, 46.5) covering at home against the Seattle Seahawks on Monday Night Football. The Lions have one of the NFL's most explosive offenses, and will be undoubtedly the best unit the Seattle defense has faced this season. Detroit has arguably the top offensive line in the NFL, and they have playmakers all over the field in Amon-Ra St. Brown, Jahmyr Gibbs, David Montgomery, and Sam LaPorta.

Defensively, the Lions have been one of the top teams in the NFL in 2024. They enter Week 4 ranked ninth in the league in scoring defense (17.7 points allowed per game) and 10th in total defense (293.3 yards allowed per game). Seattle has a perfect 3-0 record, but their opponents have posted a combined 3-6 mark this season. See who else the NFL Vegas sharps are backing in Week 4 here.

How to get sharp money Vegas NFL ATS picks for Week 4

The Vegas sharps have also targeted two other NFL games and already locked in their against the spread picks, including on a team in desperate need of a win. You can only see who they are backing in Week 4 here. 

Which NFL teams are the sharp money bettors in Las Vegas backing in Week 4? And which desperate team is getting all the attention? Visit SportsLine now to see the top NFL picks and best bets from respected professional football bettors in Las Vegas, and find out.