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College football odds, picks, bets, predictions for Week 7, 2024: Computer model loves Notre Dame, Vanderbilt

SportsLine's advanced computer model has revealed its 2024 Week 7 college football picks

· CBS Sports

Fresh off a loss to Vanderbilt last week, the No. 7 Alabama Crimson Tide will host the South Carolina Gamecocks on Saturday. The new 12-team format for the College Football Playoff gives some of the nation's top programs a little leeway this season but Alabama certainly can't afford another letdown this weekend against South Carolina. The Crimson Tide are favored by 21.5 in the latest Week 7 college football odds via SportsLine consensus.

Meanwhile, Vanderbilt is a 13-point road underdog in Kentucky coming off their first-ever win over a team ranked fifth or better in the AP Top 25. So how should you be handling those games as you place your Week 7 college football bets, and what other Week 7 college football lines should be on your radar? Before locking in any Week 7 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks, and is 8-4 on top-rated picks over the past two weeks of this season. Anyone who has followed it has seen strong returns. 

Now, it has turned its attention to the latest college football odds and Week 7 college football betting lines on the spreadmoney line and over/underHead here to see every pick.

Top college football predictions for Week 7 

One of the college picks the model is high on during Week 7: No. 11 Notre Dame (-23) cruises to a blowout win over Stanford in a 3:30 p.m. ET matchup on Saturday. It's already been a rollercoaster season for the Irish, who earned a big win over Texas A&M on the road to begin the year but then lost at home to NIU the following week. However, Notre Dame rebounded for dominant wins over Purdue and Miami (OH), then earned a 31-24 win over No. 15 Louisville two weeks ago.

Now the Irish are coming off a bye week to host Stanford and the Cardinal are coming off losses of 26 points to Clemson and 24 points to Virginia Tech. The Stanford passing attack has only averaged 5.8 yards per attempt this season and it is bound to have problems with a loaded Notre Dame defense. That is a big reason why the model predicts that the Irish cover in nearly 60% of simulations. See the rest of its Week 7 college football picks here. 

Another prediction: Vanderbilt covers as 13-point road underdogs against Kentucky in a 7:45 p.m. ET kickoff on Saturday. The Wildcats have dropped five of their last seven home games, including conference losses to South Carolina and Georgia earlier this season. They are coming off an upset road win at Ole Miss, but they have only covered the spread once in their last six home games against Vanderbilt. 

The Commodores took Missouri to double overtime as 18-point underdogs before taking down top-ranked Alabama as 23-point underdogs in the biggest win in school history. Senior quarterback Diego Pavia has 973 passing yards, a team-high 335 rushing yards, and 10 total touchdowns. The Commodores have covered the spread in five of their last six games, and they are covering in over 60% of the latest simulations for this game. See picks for every other game in Week 7 here. 

How to make college football picks for Week 7

The model has also made the call on who wins and covers in every FBS matchup in Week 7, and it's calling for a whopping 10 underdogs to win outright. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence, and which 10 underdogs win outright in Week 7? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $2,000 in profit since its inception, and find out.

College football odds for Week 7

See full Week 7 college football picks, odds, predictions here

Friday, Oct. 11

Northwestern at Maryland (-11, 45.5)

UNLV at Utah State (+18.5, 66.5)

Utah at Arizona State (+5.5, 46.5)

Saturday, Oct. 12

Clemson at Wake Forest (+20.5, 62)

South Carolina at Alabama (-21.5, 50.5)

Stanford at Notre Dame (-23, 45.5)

Texas vs. Oklahoma (+14.5, 48.5)

Penn State at USC (+3.5, 50.5)

Mississippi State at Georgia (-33.5, 54.5)

Florida at Tennessee (-14.5, 57.5)

Ole Miss at LSU (+3.5, 62.5)

Ohio State at Oregon (+3, 54)

Iowa State at West Virginia (+3, 53.5)

Kansas State at Colorado (+3.5, 55.5)