San Francisco vs. Cal Poly predictions, odds, time: 2024 college basketball picks, Nov. 5 bets from top model

SportsLine's model simulated Tuesday's San Francisco Dons vs. Cal Poly Mustangs matchup 10,000 times and reveals its CBB picks

The San Francisco Dons will host the Cal Poly Mustangs on Tuesday as both teams tip off their 2024-25 college basketball seasons. The Dons went 23-11 last season, notching a bid in the NIT, where they lost their opening game to Cincinnati in overtime. Meanwhile, the Mustangs limped to a 4-28 record a year ago, with the 28 defeats tying for the fourth-most in the country. Cal Poly enters this season with 20 straight losses, with each of those coming in conference play.

Tip-off is at 10 p.m. ET from War Memorial Gymnasium in San Francisco. The Dons are favored by 22.5 points in the latest Cal Poly vs. San Francisco odds, per SportsLine consensus. The over/under is 151.5 points. Before entering any San Francisco vs. Cal Poly picks, you'll want to see the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2024-25 season on a 153-110 betting roll (+1891) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen huge returns.    

The model has set its sights on Cal Poly vs. USF. You can head to SportsLine to see its picks. Here are several college basketball betting lines and trends for USF vs. Cal Poly:

• Cal Poly vs. San Francisco spread: Cal Poly +22.5
• Cal Poly vs. San Francisco over/under: 151.5 points
• Cal Poly vs. San Francisco money line: Cal Poly +1770, USF -5882
• USF: The Over was 11-4 for the Dons at home last season
• CP: The Over was 10-5-1 for the Mustangs on the road last season
• Cal Poly vs. San Francisco picks: See picks at SportsLine
• Cal Poly vs. San Francisco streaming: FuboTV (Try for free)

Why you should back Cal Poly

The Mustangs struggled immensely last year, but they did win their season opener. In fact, they've won their season opener in each of the last four years, giving them hope to start off the 2024-25 campaign. Additionally, this is a non-conference matchup with Cal Poly of the Big West taking on USF of the West Coast Conference, and the Mustangs were above .500 (6-5) against the spread in out-of-conference games a year ago.

Cal Poly's leading returning scorer is sixth-year player Jarred Hyder, who had 13 double-digit outings a year ago. He averaged 10.3 points and had a season-high of 21 points on Feb. 10 versus Long Beach State. The team will also welcome back Logan McLaughlin, who missed all of last season due to injury after transferring to Cal Poly. In his prior stop at New Mexico Junior College, McLaughlin was second on the team with 11.2 points and is another experienced player as he enters his fifth year. See which team to pick here.

Why you should back San Francisco

San Fran had one of the best defenses in the nation last season, ranking 21st in the nation in defensive rating. It led the WCC in steals and kept opponents under 34% from beyond the arc. The Dons also had a tendency to raise their level of play outside of the West Coast Conference as while they were just 8-10 ATS within the WCC, they were 11-4 ATS against non-conference opponents.

Marcus Williams, an All-WCC First-Team selection last year, paces USF and averaged 14 points, 3.9 assists and 3.3 rebounds last season. He has a new center flanking him in 7-footer Carlton Linguard Jr., who spent the last two years at UTSA after two seasons at Kansas State. He averaged 9.3 points, 6.2 rebounds and 1.5 blocks a year ago, notching five double-doubles. Ndewedo Newbury is also slated for a bigger role after putting up 9.4 points on 52.6% shooting in 25.8 minutes last season. See which team to pick here.

How to make San Francisco vs. Cal Poly picks

SportsLine's model has simulated Cal Poly vs. San Francisco and is leaning Under on the total, projecting 141 combined points. It also says one side of the spread hits in well over 70% of simulations. You can only get the pick at SportsLine.

So who wins San Francisco vs. Cal Poly, and which side of the spread cashes in well over 70% of simulations? Visit SportsLine now to see which side of the Cal Poly vs. San Francisco spread to jump on, all from the advanced model that is up nearly $1,900 on its college basketball picks dating back to 2023, and find out.