Madonna's brother, Christopher Ciccone, has died at age 63 from cancer. Ciccone worked with the "Vogue" singer in her early career before parting ways professionally.

Christopher Ciccone, the artist and designer who was the younger brother of Madonna, has died at the age of 63. 

Christopher Ciccone, a multihyphenate artist, dancer, designer and younger brother of Madonna, has died.

Madonna's younger brother Christopher Ciccone - who worked closely with the Queen of Pop throughout her career - has died.

Oct. 6 (UPI) -- Pop music icon Madonna's brother Christopher Ciccone has died of cancer at the age of 63, two weeks after their 81-year-old stepmother, Joan Clare Ciccone, passed away from the same disease.

Madonna is mourning the loss of her brother Christopher Ciccone, who sadly died at the age of 63, just days after their stepmother Joan Clare Ciccone passed away.

Music icon Madonna has lost her younger brother, Christopher Ciccone, who worked as a designer, artist and director throughout his career organizing concert tours, music videos, and film, to commercial, residential interior and furniture design

Music icon Madonna has lost her younger brother, Christopher Ciccone, who worked as a designer, artist and director throughout his career organizing concert tours, music videos, and film, to commercial, residential interior and furniture design

Madonna's brother, Christopher Ciccone, died on Sunday aged 53, just days after the death of the siblings' stepmother, Joan Clare Ciccone, who died after a battle with cancer

Christopher Ciccone worked closely with his sister during the early years of their careers

Madonna 's brother Christopher Ciccone passed away peacefully on October 4 surrounded by his husband Ray Thacker and their loved ones at his home in Michigan.