Duke vs. Florida State prediction, odds, line: 2024 Week 8 college football picks, Friday bets by proven model

SportsLine's model revealed its CFB picks and predictions for FSU Seminoles vs. Duke Blue Devils on Friday

The Duke Blue Devils (5-1, 1-1) revisit their conference rivalry with the Florida State Seminoles (1-5, 1-4) on Friday. Duke suffered its first loss of the season ahead of its Week 7 bye, falling 24-14 to Georgia Tech in Week 6. The Seminoles are hoping their own Week 7 bye will help them turn the season around as they most recently tallied a 29-13 loss to Clemson.

Kickoff at Wallace Wade Stadium in Durham, N.C., is scheduled for 7 p.m. ET. The Blue Devils are 3-point favorites in the latest Florida State vs. Duke odds via SportsLine consensus, while the over/under for total points scored is 42. Duke is a -150 (risk $150 to win $100) favorite on the money line, with Florida State listed as a +125 underdog. Before making any Duke vs. Florida State picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks and it is 12-5 on top-rated picks over the past three weeks of this season. Anyone who has followed it on betting sites has seen strong returns.

Now, the model has dialed in on Duke vs. FSU and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football betting lines and trends for FSU vs. Duke.

• Duke vs. Florida State spread: Blue Devils -3
• Duke vs. Florida State over/under: 42.5 points 
• Duke vs. Florida State money line: Duke -150, FSU +125
• Duke: 2-1-2 ATS this season 
• FSU: 2-4-0 ATS this season 
• Duke vs. Florida State picks: See picks here
• Duke vs. Florida State streaming: FuboTV (Try for free)

Why Florida State can cover

The Seminoles enter another game without quarterback DJ Uiagalelei, who sustained a hand injury against SMU in Week 5 and is out for at least several more weeks and perhaps the entire season. Freshman quarterback Brock Glenn was solid in his start against Clemson, however, throwing for 228 yards with two touchdowns and one interception. Glenn is expected to improve on that performance with the bye week to prepare for the Blue Devils.

FSU has an additional edge since it has never lost to Duke. The Seminoles are 22-0 against the Blue Devils lifetime, most recently defeating the Blue Devils in Tallahassee 38-20 last season. In the teams' last two meetings in North Carolina, FSU has outscored Duke 58-26 including a 17-10 win at Wallace Wade Stadium in 2017. See who to back at SportsLine.

Why Duke can cover

The Blue Devils have an opportunity to get their first win in program history against the Seminoles thanks to their sturdy defense. Duke's defense ranks second in the ACC in total yards allowed per game (309.3) and points allowed per game (17.5). Meanwhile, Florida State's offense ranks last in the conference in average points per game (14.8) and touchdowns (10).

Duke has also gotten positive production from quarterback Maalik Murphy and running back Star Thomas, who are both in their first seasons with the team after transferring. Murphy has thrown for 1,431 yards with 14 touchdowns and just five interceptions, while Thomas has run the ground game with 528 rushing yards on 113 carries and scored three touchdowns. See who to back at SportsLine.

How to make Duke vs. Florida State picks

SportsLine's model is leaning Over on the total, projecting 47 combined points. It also says one side of the spread hits over 50% of the time. You can see the model's pick at SportsLine.

So who wins FSU vs. Duke, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.