Tulane vs. Charlotte prediction, odds, spread, line: 2024 college football Week 10 picks by proven model

SportsLine's model revealed its CFB picks and predictions for Charlotte 49ers vs. Tulane Green Wave on Thursday

The Tulane Green Wave look to continue their undefeated season in American Athletic Conference play when they take on the Charlotte 49ers on Thursday night. Tulane is coming off a 45-27 win over North Texas on Saturday to improve to 6-2 and 4-0 in the AAC. North Texas had a chance at completing a miracle comeback with 14 points in the fourth quarter, but Tulane recovered an onside kick with 37 seconds left to secure the victory. Charlotte is coming off a 33-28 loss to Memphis on Saturday to fall to 3-5 and 2-2 in the AAC for its second straight loss. This is the first meeting between the programs as Charlotte is playing just its second season in the ACC.

Kickoff is set for 7:30 p.m. ET from Jerry Richardson Stadium in Charlotte, N.C. The Green Wave are 16.5-point favorites, according to the latest Charlotte vs. Tulane odds via the SportsLine consensus, while the over/under for total points scored is 55.5. Before making any Tulane vs. Charlotte picks, you need to see the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

Now, the model has dialed in on Charlotte vs. Tulane and just revealed its coveted picks and predictions. You can head to SportsLine now to see the model's picks. Here are the college football betting lines and trends for Tulane vs. Charlotte:

• Charlotte vs. Tulane spread: Green Wave -16.5
• Charlotte vs. Tulane over/under: 55.5 points 
• Charlotte vs. Tulane money line: Green Wave -758, Owls +515
• TUL: Tulane is 4-1 ATS over its last five games 
• CHA: Charlotte is 3-1 ATS over its last four games
• Charlotte vs. Tulane picks: See picks here
• Charlotte vs. Tulane streaming: FuboTV (Try for free)

Why Tulane can cover

The Green Wave have been dominant in AAC play this season, going 4-0 with victories by an average of 27 points. Tulane is winning behind the dynamic rushing ability of sophomore running back Makhi Hughes, who has rushed for more than 115 yards in four of his last five games. Hughes is averaging 117.4 rushing yards per contest, including 167.5 yards over his last two games. The speedy 5-foot-11 back rushed for 195 yards on 30 carries for 6.5 yards per rush and a touchdown against North Texas last week.

Tulane rushes on 64.5% of plays, the fourth-most in college football, and ranks 10th in rushing yards (213.3 per game). Those are largely scripted running back carries as redshirt freshman quarterback Darian Mensah isn't much of a runner. He's averaging three rushes per game over his last four contests. Charlotte ranks outside the top 100 in nearly every defensive rushing statistic, including 118th in rushing yards allowed per game (203.6) in what appears to be a challenging matchup for the 49ers. See who to back at SportsLine.

Why Charlotte can cover

Although Charlotte has lost back-to-back AAC contests, the 49ers hung with Memphis as 16-point underdogs before losing 33-28 last week. Charlotte tied the score at 21 with two touchdowns over the first seven minutes of the fourth quarter before Memphis had a touchdown, field goal and safety over the final two minutes. The 49ers proved they can score quickly, even when trailing, as the 49ers had a 57-yard pass before an 18-yard touchdown run by Hahsaun Wilson gave Charlotte a 28-24 lead with 1:20 left in the fourth quarter.

Memphis responded with a seven-play, 75-yard touchdown drive over 49 seconds to exit with the victory, but the 49ers showed they can be in the mix until the final whistle even as substantial underdogs. Charlotte threw two interceptions against Memphis and if the 49ers can limit those mistakes, they can certainly cover this 16.5-point spread. See who to back at SportsLine.

How to make Charlotte vs. Tulane picks

SportsLine's model is leaning Over on the total, projecting 62 combined points. It also says one side of the spread hits in almost 70% of simulations. You can see the model's pick at SportsLine.

So who wins Tulane vs. Charlotte, and which side of the spread hits almost 70% of the time? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on top-rated spread picks since its inception, and find out.